jeudi 28 mai 2020

Offre de contrat doctoral du01/10/2020au 30/09/2023

Titre: "Le goût du risque chez l’enfant: la prise de risque économique et physique entre 7 et 9 ans"Description du projet de thèse:L’attitude face au risque change en fonction des âges de la vie. L’étude des décisions économiques, c’est-à-dire des décisions motivées par l’obtention de gains éventuels, met ainsi en évidence des différences comportementales entre les enfants et les adultes. Sur le plan du comportement économique, nous observons chez les enfants âgés entre 5 et 8 ans une appétence au risque. En effet, à la différence des adultes, les enfants préfèrent les options risquées en situation de gain. Sur le plan de la prise de risque physique, nous observons également des spécificités comportementales chez l’enfant. Ainsi, malgré une moindre exposition au trafic routier, les enfants âgés entre 5 et 9 ans représentent le cinquième des piétons tués surla route. Une sous-estimationdu risque se trouve à l’origine de nombreux accidents de circulation, en particulier au niveau de la perception de la dangerosité d’une route en contexte de traversée pédestre. Le présent projet de thèse porte sur l’étude des mécanismes psychologiques à l’œuvre dans la prise de risque chez les enfants âgés entre 7 et 9 ans. Pour comprendre la manière dont les enfants appréhendent le risque économique, il faut introduire l’existence de biais comportementaux tels que l’appétence au risque en situation de gain (cf., Rivière, Kurt & Meunier2019JournalofNeuroscience,Psychology,andEconomics; Rivière, Stomp, Augustin, Lemasson & Blois-Heulin2018DevelopmentalPsychobiology). L’objectif de ce projet de thèse est d’explorer le rapport au risque chez les enfants et d’identifier les déterminants de leur conduite à risque. Mots-clés: comportement de choix; prise de décision; risque; économie comportementaleFinancementAllocation doctorale de 100% cofinancée par la Région Normandie et L’Union européenneavec le Fonds Européen de Développement Régional (FEDER).EncadrementL’encadrementsera réalisé par James Rivière, maître de conférences HDR en psychologie du développement (laboratoire CRFDP) etRégis Thouvarecq, professeur en STAPS(laboratoire CETAPS), Université de Rouen Normandie.Compétences attenduesTitulaire d’un Master 2, le candidat présentera de fortes compétences en méthodologie expérimentale et en analyse statistique des données.Dépôt de candidatureLes personnes candidates enverrontun CV détaillé,une lettre de motivation, une lettre de recommandation du directeur de mémoire (M1 et/ou M2) ainsi qu’unrelevé de notes universitaires.Contacts:James Rivière(james.riviere@univ-rouen.fr)Régis Thouvarecq (regis.thouvarecq@univ-rouen.fr)

Animal Biologist - NIH - Bethesda, MD

Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers.  Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking an Animal Biologist to work onsite with the National Institutes of Health in Bethesda, MD.

This is a long-term contract position which offers:
·         Competitive salary with comprehensive benefit package
·         Tremendous growth opportunity
·         Opportunity to work at NIH, the world's foremost medical research center
·         Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com

TASKS. The contractor shall:
·         Coordinate all training for monkeys that are not yet enrolled in a project under an SCNI investigator; handle and train large (6-15 kg) rhesus macaque monkeys; bring the animal from the cage into a special chair, safely restrain the animal; teach the animal to respond to a variety of different visual stimuli using operant conditioning; acclimatize animals to the mock-magnet training environment so that the animals grow accustomed to experiencing an enclosed space with loud noises.
·         Monitor SCNI’s marmoset monkey colony; monitor health, conduct ultrasound, care of babies.
·         Assist SCNI’s research with marmoset monkeys; catch the animal from the cage, acclimate the animal to the experimental setup, restrain the animal, give injections; assist with anesthesia in marmosets and rats; prepare implants and implant head restraints; check implants of animals and suggest/help cleaning of the implant if necessary; record chambers and electrode arrays; analyze and evaluate preliminary behavioral data from monkey experiments and report findings; sterilize and clean surgical tools; participate in, prepare for and clean up following aseptic surgery; construct and sterilize small elements used in electrophysiology recordings such as electrode arrays, guide tubes, and cannulae.
·         Perform basic level operation of the MR scanner for both structural and functional imaging; maintain the laboratory 3D printer; coordinate with machine shops and/or assist staff coordinate with outside companies for special 3D printing; prepare printing and post-print processing of 3D models; coordinate lab/machine shop interactions, scheduling meetings when needed.
·         Work with lab heads on editing and submission of animal study proposals; assist incoming laboratory members with initial administrative requirements; advise incoming laboratory members in procedures as appropriate; assist staff with ordering and assembly of equipment; assist staff to organize and document all vendors and purchases to facilitate future orders; coordinate inventory throughout the lab, replenish supplies in a timely manner; book meeting room for laboratory meetings; coordinate presenter schedule

REQUIREMENTS. The contractor must have:
·         Master’s degree in Biological Sciences or a related discipline; three (3) years of specialized experience plus a Bachelor’s degree is equivalent to a Master’s degree.
·         Nine (9) years of experience in Molecular Biology, Immunocytochemistry, or a related field. Demonstrates experience in performing surgical procedures with small animals.
·         Experience with Microsoft Office Suite (MS Word, Excel, Outlook).
·         Expertise in programming in Matlab, Java, or C preferred.
·         Sufficient in stature and strength to be able to control a 15kg animal.
·         No general apprehension working with monkeys.
·         Experience with aseptic surgery.
·         Strong communications skills, both oral and written.
·         Excellent analytical, organizational and time management skills.

PLEASE APPLY ONLINE.
Note that the phone number for our NIH branch is not listed.  Due to the high volume of inquiries, we regret that we cannot accept phone calls.  All qualified candidates will be contacted.

Why Kelly®?

Looking to connect with premier government agencies or the top 25 federal government contractors? Kelly® Government offers a variety of full-time, project (SOW), seasonal, and surge support opportunities in science, engineering, technical, professional, and administrative support roles. Our experts will find you the opportunity that fits your schedule and interests and handle the details of transferring and processing all levels of security clearances. It’s just another way we make the job search work for you.

About Kelly®

Kelly connects talented people to companies in need of their skills in areas including Science, Engineering, Education, Office, Contact Center, Light Industrial, and more. We’re always thinking about what’s next in the evolving world of work, and we help people ditch the script on old ways of thinking and embrace the value of all workstyles in the workplace. We directly employ nearly 500,000 people around the world, and we connect thousands more with work through our global network of talent suppliers and partners in our outsourcing and consulting practice.
Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity Equal Employment Opportunity is The Law.

mardi 26 mai 2020

Postdoctoral Fellowship Available in Primate Behavioral Neuropathology

A postdoctoral position is available in the laboratory of Carol Shively in the Department of Pathology, Section on Comparative Medicine at Wake Forest School of Medicine to study social and biological factors that affect age-related changes in behavior and neurobiology in nonhuman primates (NHPs). The Fellow will work with a multidisciplinary team on the development of a NHP model of social and dietary factors that promote neuropathologic changes characteristic of Alzheimer’s disease, and determine functional correlates. The fellow also will be encouraged to make use of extensive NHP data, tissue, and imaging repositories that provide a rich source of research projects ready for analysis and publication.

Candidates must have a Ph.D. in the social or biological sciences. Requirements include outstanding skills in data analysis, written and oral communication, and the ability to work both independently and in a multidisciplinary team-oriented environment. Candidates with experience in NHP behavior and neurobiology are particularly encouraged to apply. The position is available for up to three years and compensation will follow NIH postdoctoral stipend levels.

Applicants should submit via email a letter of interest outlining experience and research goals, as well as a CV and the names and complete contact information of three references to:

Carol A. Shively, Ph.D., Professor 
Department of Pathology/Comparative Medicine 
Wake Forest School of Medicine 
Medical Center Boulevard
Winston-Salem, NC 27157 

Sujet de thèse sur les stratégies de reproduction alternatives chez le gobie

DOCTORAL SCHOOL E2M2
E2M2 COMPETITIVE RECRUITMENT FOR DOCTORAL CONTRACTS / CAMPAIGN 2020
Subject: Alternative reproductive tactics in structured populations of invasive fish species
Scientific Research theme: Evolutionary biology, Population biology, Ecophysiology
PhD supervisor (NOM Prénom) :
DECHAUME-MONCHARMONT F.-Xavier
Research unit:
LEHNA, UMR 5023, Lyon
Co-supervisor (NOM Prénom):
MEDOC VincentResearch unit:
ENES/CRNL, UMR CNRS 5292, St-Etienne
E-mail: fx.dechaume@univ-lyon1.fr E-Mail : vincent.medoc@univ-st-etienne.fr
 

In  polygynous  or  polygynandrous  species,  strongly  biased  operational  sex-ratios  (OSR) frequently induce high male reproductive skew. Such an intense male -male competition over access to females leads to the evolution of strategies characterized by high-competitiveness1, dominance,  territoriality  and  aggressive  partner  monopolization.  Yet,  sympatric polymorphisms  in which several alternative mating tactics  co-exist as the result of  frequency dependant games2.  Population of dominant morphs  in which males actively defend territory or females can be invaded by sneaker males, which are typically smaller and less aggressive than dominant males.  This  existence of multiple optimal investments  in competitiveness is  the result of the trade-off between being able to acquire many or high-quality resources and the ability to make the best use of these resources. Sneaker males typically attain many extra-pair copulations  without  investing  in  territorial  defence,  thus  achieving  reproductive  success equivalent to the one of more dominant morphs.
During  expansion  of  their  range,  invasive  species  experience  contrasted  conditions along the invasion gradient: the evolutionary pressures are rather different  at the invasion front  and  at the range-core. For example, low densities at the edge of the range mean that males should experience lower sexual  competition. Thus, investment into reproduction may trade-off with adaptations for more rapid dispersal: recent invasion unleashes evolutionary and ecological pressures and should favour low resource allocation to reproduction3.

Biological  model  and  field  work.  We  propose  to  explore  the  evolution  of  alternative reproductive  tactics  in  a  rapidly  invasive  fish  species,  the  round  goby  Neogobius melanostomus. Round gobies, originated from the Ponto-caspian region, were introduced by boat water ballasts 20 years ago in the region of the Great Lakes in North America, where this species  is  now  ubiquitous  and  has  dramatic  consequences  on  the  native  fauna4. More recently,  populations are now settled  in  Western Europe  rivers, notably in France: the invasion front is currently located in the rivers of Alsace-Lorraine in North-East of France5.  The invasion front  is  expected  to  reach  the  river  Rhône  and  the  major  alpine  lakes  (Lake  Geneva,  Lake Annecy, Lake Bourget) in the next few years.
In this species,  a polymorphism of reproductive strategies has been characterized by the presence in the same  population  of several alternative tactics of reproduction6,7: certain so-called Guarder  males invest substantially in reproduction (defence of the partner and the territory,  nest  building,  parental  care),  and  other  males  called  Sneakers  favour  a  lower investment  in  reproduction  and  seeking  to  obtain  st ealthy  copulations,  less  effective  than those of the Guarders but also less costly in time and energy.
This biological model provides unique opportunity to compare behavioural, ecological and  physiological  performances  between  populations  at  different  stages  of  the  invasive process.  This  research  project  will  involve  several  field  trips  in  North-East  of  France  for population  sampling  and  in  natura  behavioural  observations.  The  aim  of  the  project  is  to decipher the underlying constraints controlling the alternative reproductive tactics and their local ecological success. To this end, different populations will be sampled along the invasion gradient  and  compared  using  a  wide  range  of  integrative  tools  including  behavioural phenotyping,  measures  of  acoustic  communication  using  hydrophone8 and  in  vivo ecophysiology performances (swim ability, oxygen consumption,  fecundity, aging, life span).
We also intend to  compare  the competitive ability of  these  morphs  (Guarder  vs.  Sneaker)  in terms  of  foraging  or  territoriality  against  other  non-invasive  species  and  therefore  gain knowledge  that  will  enhance  the  management  and  conservation  of  our  freshwater ecosystems.
Supervision. This PhD thesis will be co-supervised by a behavioural ecologist specialized in the evolution of mating tactics (FXDM, Lehna, Lyon), an ecologist with special interest in foraging strategy and acoustic communication in fish species (VM, ENES – CNRL, Saint-Etienne), and an ecophysiologist (Loic Teulier,  Lehna, Lyon) specialized in  bioenergetic efficiency in fish species.
 
Applicants. Applicants should have a Master (MSc) and a strong background in at least one of the  following areas:  animal behaviour, ecology,  or ecophysiology. Solid knowledge in statistics would be appreciated.
References : 1 Dechaume-Moncharmont, F.-X. et al. Animal Behaviour 114, 249–260 (2016).
2 Baldauf, S. A. et al. Nature Communications 5, 5233 (2014). 3 Friesen, C. R. et al. Biol. Lett.
15,  20190339  (2019).  4  Kornis,  M.  S.  et  al.  Journal  of  Fish  Biology  80,  235–285  (2012).
5 Manné, S.  et al.  Knowl. Managt. Aquatic Ecosyst.  02 (2013).  6  Myles-Gonzalez, E.  et al.
Behav Ecol 26, 1083–1090 (2015). 7 McCallum, E. S. et al. Can. J. Fish. Aquat. Sci. 76, 1562–
1570 (2018). 8 Zeyl, J. N. et al. Journal of Experimental Biology 216, 1075–1084 (2013)

Sujet de thèse Université Caen Normandie, Neurobiologie céphalopode

Titre du projet de thèse / Title of the PhD thesis project:Circuits cérébraux de la mémoire chez un céphalopodeBrain circuits involved in memory in a cephalopod speciesUnité de recherche / Research Unit :UMR 6552 CNRS ETHOS, Université de Caen Normandie (https://ethos.univ-rennes1.fr/)équipe NECC: Neuroéthologie des Céphalopodes Direction de thèse proposée / proposed PhD mentor(s) :Cécile BELLANGER et Christelle JOZET-ALVESSujet de la thèse / Subject of the PhD thesis:Pour comprendre l'évolution des capacités cognitives, il reste crucial de déterminer quels aspectsdes processus cognitifs sont partagés entre les espèces, mais aussi de comparer similitudes etdifférences entre les substrats neuronaux sous-jacents.Pour une telle approche comparative et neurobiologique de la cognition, les céphalopodes semblentêtre des espèces très prometteuses : i) ils possèdent des structures cérébrales très différentes decelles des vertébrés ; ii) ils présentent des capacités cognitives extraordinairement sophistiquées quisont apparues indépendamment de la lignée des vertébrés. Différents types de mémoire ont été misen évidence chez les céphalopodes : empreinte1, mémoires associative2, de travail, spatiale3 et detype épisodique4. Sur la base d'études antérieures (approches lésionnelles5,6, histochimiques7 ouélectrophysiologiques8), le complexe du lobe vertical (VLc) est considéré comme un circuitcérébral clé des processus d'apprentissage et de mémoire. Néanmoins, l'activation spatiale ettemporelle du VLc au cours de la mémorisation et du rappel reste inconnue ainsi que sa spécificitépar rapport à un type de mémoire particulier. Nous proposons donc d'aborder ces questions chez laseiche en étudiant l'expression de gènes précoces immédiats (IEG) connus pour être impliqués dansles processus mnésiques. Le projet de thèse sera subdivisé en 3 parties consécutives :1) Localiser les zones cérébrales activées lors de la mémorisation d’un paradigme simple (ex:mémoire associative).2) Évaluer les changements dynamiques de l'activation du cerveau liés aux différentes étapes de dela mémorisation (acquisition, consolidation et rappel).3) Comparer les réseaux neuronaux activés par différents types de mémoire.Ce projet s'inscrit dans la continuité d'une collaboration récente sur la détection d’IEG parhybridation in situ entre EthoS et l'UMR BOREA (Muséum National d'Histoire Naturelle). Il estcomplémentaire d'un projet de recherche déjà financé (ANR COMETT ; 2019-2022 ; PI : C. Jozet-Alves) qui prendra en charge le coût des expériences.To understand the evolution of cognitive abilities, it remains crucial to determine what aspects ofcognitive processes are shared among species, but also to compare the similarities and differencesbetween underlying neural substrates.In this comparative framework, cephalopods appear to be highly promising species to study theneurobiology of cognition: i) they possess markedly different brain structures than vertebrates; ii)they exhibit extraordinarily sophisticated cognitive abilities which have arisen independently of thevertebrate lineage. Different types of memory have been evidenced in cephalopods: i.e.
imprinting1, associative memory2, working memory, spatial memory3, episodic-like memory4. Basedon previous studies (lesional5,6, histochemical7 or electrophysiological8 approaches), the verticallobe complex (VLc) is considered as a key brain circuit of the learning and memory systems.Nevertheless, the spatial and temporal activation of the VLc during memory formation and recallas well as its specificity toward a memory type remain unknown. Thus, we propose to address theseissues in the cuttlefish by assessing the expression of immediate early genes (IEG) known to beinvolved in memory processes. The PhD project will be subdivided into 3 consecutive parts:1.Mapping the brain regions activated during memory formation in a simple paradigm (e.g.associative memory)2.Assessing the dynamic changes in brain activation related to the different steps of learning and memory formation (i.e. acquisition, consolidation and recall).3.Comparing activated neural networks driven by different types of memory.This project will be the continuity of a recent collaboration on IEG detection through in situ hybridization between EthoS and BOREA research unit (Muséum National d’Histoire Naturelle) andis complementary to a funded research project (ANR COMETT; 2019-2022; PI: C. Jozet-Alves) that will support the experimental costs.Expérience et formation souhaitée du candidat / Experience and education desired for the applicant:Le·a candidat·e devra avoir une formation en Neurobiologie et potentiellement en Expérimentationanimale. Il est souhaitable qu’il/elle ait de bonnes notions (expérience) sur la cognition et l’étudedu comportement animal.The candidate should have a background in Neurobiology and potentially in AnimalExperimentation. A good knowledge (experience) of Cognition and the study of Animal Behavior isrecommended.Contacts / Contacts : cecile.bellanger@unicaen.fr (Tél. : 02 31 56 68 79)christelle.alves@unicaen.fr (Tél. : 02 31 56 68 78) Pour candidater / to apply:avant le 31 mai 2020/ deadline 2020 may 31st Envoyer par email: un CV détaillé + une lettre de motivation + relevé de notes et classement des 2années de master avec l’effectif de la promotion (M1 et 1er semestre de M2 si en cours) àcecile.bellanger@unicaen.fr et christelle.alves@unicaen.frSend by email: a detailed CV + a motivation letter + marks of the 2 years of master degree and ranking with the total number of students (first year and first term of the 2d year if not completed) to cecile.bellanger@unicaen.fr and christelle.alves@unicaen.fr