jeudi 15 octobre 2015

TWO PhD PROJECTS: SEXUAL CONFLICT & DNA METHYLATION IN SOCIAL INSECTS, MELBOURNE

Two PhD projects - commencing 2016 (typically February)

Luke Holman lab, School of Biosciences, University of Melbourne.

I am seeking one or two PhD students to join ongoing projects involving evolution, sex and sociality in insects, which are funded by the Australian Research Council and the University of Melbourne. I am particularly keen to recruit students interested in working with next generation sequencing data (both projects) or large-scale insect experiments (project 1).

Project 1: Genetics of sexual conflict in beetles

Sexual selection research commonly talks about good genes, but just who are these genes good for? There is evidence that alleles that produce a high-fitness female do not necessarily make a high-fitness female, and vice versa. This is termed intralocus sexual conflict, and it has far-reaching evolutionary consequences. Using experimental evolution experiments coupled with next-generation sequencing in Tribolium flour beetles, we will work out which traits are under strong intralocus conflict, which ecological and evolutionary factors determine the strength of the conflict, and which genes are contested territory in the battle of the sexes.

Project 2: DNA methylation in social insects

If the genome is like a printed instruction book for building an organism, DNA methylation is like pencil notes in the margins that allow for reversible modifications to the design. Social insects (bees, ants, wasps, termites) have two castes queens and workers and recent evidence suggests that caste (and other, more subtle differences, e.g. between different types of workers) is under the control of DNA methylation. Using experiments with ant and bee colonies as well as whole genome bisulphite sequencing, we will build on exciting new results from my lab, and study the interplay between pheromones and DNA methylation.

Requirements

Successful applicants will be assisted in applying for an Australian Postgraduate Award (for Australians) or an International Postgraduate Research Scholarship (for Internationals) through the University of Melbourne. To be competitive, a First-class Honours or Masters Degree (or international equivalent) or publication in international journals are essential. The APA and IPRS applications are short, but the deadline is soon: 31st October 2015. Thus, please send applications by 19th October or earlier.

To apply, please send A) A brief letter outlining your research interests; B) an academic CV; C) your academic transcript/grades; D) contact details of two referees (including a previous research supervisor).

For further information, and to submit applications, please contact Luke Holman directly.

Luke Holman

Tel: +61 2 612 53611