Single unit and LFP analysis in human epileptic
patients
Institut du Cerveau et de la Moelle
Epinière, Paris, France
The « EpiMicro » group,
within the Pr Stephane Charpier’s team, at the Brain and
Spine Institute (ICM) in Paris, is looking for a
postdoctoral fellow to participate in a project on
intracerebral recordings with macro and microelectrodes in
epileptic patients. The ICM is a recently created institute
focusing on basic and translational research in neuroscience
and is located in the heart of Paris within the largest
European hospital.
The general goal of this
project is to improve knowledge on pathophysiology of
epilepsy, in particular the interictal events and the
epileptic seizures. With the development of intracerebral
recordings with microelectrodes in our epileptic patients,
we are now able since several years to perform continuous
intracerebral recordings at different scales, from usual
macroelectrodes to single neuron recordings, in the
interictal period but also during seizures, in multiple
intracerebral areas.
The main role of the
position will be to perform electrophysiological analysis of
intracerebral signals at different periods: during the
interictal period and preictal period and to study the link
with multiunit/single unit activities in cortical areas.
The doc /post-doc will be
integrated in a multidisciplinary team including
researchers, engineers, clinical electrophysiologists,
neuroradiologists and neurosurgeons. He/she will receive a
full assistance from an engineer for the data acquisition
and storage. In addition, he/she will have inputs from
several researchers/methodologists in signal analysis.
The candidate should have a
PhD or equivalent in Signal analysis or Neuroscience related
field. Expertise in signal processing and good analytical
skills (MATLAB) are required, notably in spike sorting
analysis. Since the analytic approaches needed for this
study have been extensively developed and used in animals,
previous experience in animal
in vivo or in vitro experiments is a plus.
The starting date is November
2017. The proposition is for an initial period of 24
months with possible renewal. The competitive salary will be
according to experience. The candidate will also have access
to the French system benefits.
Keywords : intracerebral
recordings, microelectrodes, epileptic patients, spike
sorting
Thanks for forwarding a CV,
a cover letter and names of 2 references to :
Pr Vincent Navarro
vincent.navarro@aphp.fr